David Snead
I am a research associate in the Kavran Lab, where I take a structural and biochemical approach to study the molecular mechanisms underlying protein protein function and dysfunction. I am currently working to understand the molecular mechanisms of endocrine resistance by HER2 in ER+ breast cancer. For my postdoctoral work in the laboratories of Dr. Samara Reck-Peterson and Dr. Andres Leschziner at UCSD, I applied cryoEM and single molecule TIRF to study the interaction of the Parkinson’s Disease-associated protein LRRK2 with microtubules. My graduate work in the laboratory of Dr. David Eliezer at Weill Cornell Medicine applied solution state protein NMR to characterize the interaction of the presynaptic protein complexin with lipid membranes. I am excited to continue to uncover at the molecular level how proteins function, and how they cause disease.